RNA-seq analysis of the response of plant-pathogenic oomycete Phytophthora parasitica to the fungicide dimethomorph.
Identifieur interne : 000342 ( Main/Exploration ); précédent : 000341; suivant : 000343RNA-seq analysis of the response of plant-pathogenic oomycete Phytophthora parasitica to the fungicide dimethomorph.
Auteurs : Kaiqiang Hao [République populaire de Chine] ; Beisen Lin [République populaire de Chine] ; Fuzhao Nian [République populaire de Chine] ; Xi Gao [République populaire de Chine] ; Zhong Wei [République populaire de Chine] ; Gang Luo [République populaire de Chine] ; Yachun Lu [République populaire de Chine] ; Mingxian Lan [République populaire de Chine] ; Jinguang Yang [République populaire de Chine] ; Guoxing Wu [République populaire de Chine]Source :
- Revista Argentina de microbiologia [ 0325-7541 ]
Descripteurs français
- KwdFr :
- ARN messager (biosynthèse), ARN messager (génétique), Alignement de séquences (MeSH), Espèces réactives de l'oxygène (MeSH), Fongicides industriels (pharmacologie), Gene Ontology (MeSH), Maladies des plantes (parasitologie), Morpholines (pharmacologie), Paroi cellulaire (métabolisme), Perméabilité des membranes cellulaires (effets des médicaments et des substances chimiques), Perméabilité des membranes cellulaires (génétique), Phytophthora (effets des médicaments et des substances chimiques), Phytophthora (génétique), Protéines de transport (biosynthèse), Protéines de transport (génétique), Réaction de polymérisation en chaine en temps réel (MeSH), Régulation de l'expression des gènes (effets des médicaments et des substances chimiques), Stress oxydatif (génétique), bêta-Glucanes (analyse).
- MESH :
- analyse : bêta-Glucanes.
- biosynthèse : ARN messager, Protéines de transport.
- effets des médicaments et des substances chimiques : Perméabilité des membranes cellulaires, Phytophthora, Régulation de l'expression des gènes.
- génétique : ARN messager, Perméabilité des membranes cellulaires, Phytophthora, Protéines de transport, Stress oxydatif.
- métabolisme : Paroi cellulaire.
- parasitologie : Maladies des plantes.
- pharmacologie : Fongicides industriels, Morpholines.
- Alignement de séquences, Espèces réactives de l'oxygène, Gene Ontology, Réaction de polymérisation en chaine en temps réel.
English descriptors
- KwdEn :
- Carrier Proteins (biosynthesis), Carrier Proteins (genetics), Cell Membrane Permeability (drug effects), Cell Membrane Permeability (genetics), Cell Wall (metabolism), Fungicides, Industrial (pharmacology), Gene Expression Regulation (drug effects), Gene Ontology (MeSH), Morpholines (pharmacology), Oxidative Stress (genetics), Phytophthora (drug effects), Phytophthora (genetics), Plant Diseases (parasitology), RNA, Messenger (biosynthesis), RNA, Messenger (genetics), RNA-Seq (MeSH), Reactive Oxygen Species (MeSH), Real-Time Polymerase Chain Reaction (MeSH), Sequence Alignment (MeSH), beta-Glucans (analysis).
- MESH :
- chemical , analysis : beta-Glucans.
- chemical , biosynthesis : Carrier Proteins, RNA, Messenger.
- chemical , genetics : Carrier Proteins, RNA, Messenger.
- drug effects : Cell Membrane Permeability, Gene Expression Regulation, Phytophthora.
- genetics : Cell Membrane Permeability, Oxidative Stress, Phytophthora.
- metabolism : Cell Wall.
- parasitology : Plant Diseases.
- chemical , pharmacology : Fungicides, Industrial, Morpholines.
- Gene Ontology, RNA-Seq, Reactive Oxygen Species, Real-Time Polymerase Chain Reaction, Sequence Alignment.
Abstract
Phytophthora parasitica is an important oomycete that causes disease in a variety of plants, dimethomorph fungicides being specific for oomycetes. The aim of this study was to use RNA-seq to rapidly discover the mechanism by which dimethomorph acts in the treatment of P. parasitica. We found that the expression of 832 genes changed significantly after the dimethomorph treatment, including 365 up-regulated genes and 467 down-regulated genes. According to the Gene Ontology (GO) enrichment analysis, pathway enrichment and verification test results, the following conclusions are obtained: (i) the treatment of P. parasitica with dimethomorph causes changes in the expression levels of genes associated with the cell wall and cell wall synthesis; (ii) dimethomorph treatment results in reduced permeability of the cell membrane and changes in the expression of certain transport-related proteins; (iii) dimethomorph treatment increased reactive oxygen species and reduced the expression of genes related to the control of oxidative stress.
DOI: 10.1016/j.ram.2018.08.007
PubMed: 30670299
Affiliations:
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Le document en format XML
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Tobacco Research Institute of the Chinese Academy of Agricultural Sciences, Qingdao, Shandong 266101, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>State Key Laboratory for Conservation and Utilization of Bio-Resources in Yunnan, Yunnan Agricultural University, Kunming 650201, China; Tobacco Research Institute of the Chinese Academy of Agricultural Sciences, Qingdao, Shandong 266101</wicri:regionArea><wicri:noRegion>Shandong 266101</wicri:noRegion></affiliation></author><author><name sortKey="Lin, Beisen" sort="Lin, Beisen" uniqKey="Lin B" first="Beisen" last="Lin">Beisen Lin</name><affiliation wicri:level="1"><nlm:affiliation>Tobacco Science Research Institute of Baise Tobacco Company, Baise, Guangxi 533000, China; Hainan Provincial Branch of China National Tobacco Corporation, Haikou, Hainan, 571100, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Tobacco Science Research Institute of Baise Tobacco Company, Baise, Guangxi 533000, China; Hainan Provincial Branch of China National Tobacco Corporation, Haikou, Hainan, 571100</wicri:regionArea><wicri:noRegion>571100</wicri:noRegion></affiliation></author><author><name sortKey="Nian, Fuzhao" sort="Nian, Fuzhao" uniqKey="Nian F" first="Fuzhao" last="Nian">Fuzhao Nian</name><affiliation wicri:level="1"><nlm:affiliation>State Key Laboratory for Conservation and Utilization of Bio-Resources in Yunnan, Yunnan Agricultural University, Kunming 650201, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>State Key Laboratory for Conservation and Utilization of Bio-Resources in Yunnan, Yunnan Agricultural University, Kunming 650201</wicri:regionArea><wicri:noRegion>Kunming 650201</wicri:noRegion></affiliation></author><author><name sortKey="Gao, Xi" sort="Gao, Xi" uniqKey="Gao X" first="Xi" last="Gao">Xi Gao</name><affiliation wicri:level="1"><nlm:affiliation>State Key Laboratory for Conservation and Utilization of Bio-Resources in Yunnan, Yunnan Agricultural University, Kunming 650201, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>State Key Laboratory for Conservation and Utilization of Bio-Resources in Yunnan, Yunnan Agricultural University, Kunming 650201</wicri:regionArea><wicri:noRegion>Kunming 650201</wicri:noRegion></affiliation></author><author><name sortKey="Wei, Zhong" sort="Wei, Zhong" uniqKey="Wei Z" first="Zhong" last="Wei">Zhong Wei</name><affiliation wicri:level="1"><nlm:affiliation>Tobacco Science Research Institute of Baise Tobacco Company, Baise, Guangxi 533000, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Tobacco Science Research Institute of Baise Tobacco Company, Baise, Guangxi 533000</wicri:regionArea><wicri:noRegion>Guangxi 533000</wicri:noRegion></affiliation></author><author><name sortKey="Luo, Gang" sort="Luo, Gang" uniqKey="Luo G" first="Gang" last="Luo">Gang Luo</name><affiliation wicri:level="1"><nlm:affiliation>Tobacco Science Research Institute of Baise Tobacco Company, Baise, Guangxi 533000, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Tobacco Science Research Institute of Baise Tobacco Company, Baise, Guangxi 533000</wicri:regionArea><wicri:noRegion>Guangxi 533000</wicri:noRegion></affiliation></author><author><name sortKey="Lu, Yachun" sort="Lu, Yachun" uniqKey="Lu Y" first="Yachun" last="Lu">Yachun Lu</name><affiliation wicri:level="1"><nlm:affiliation>Tobacco Science Research Institute of Baise Tobacco Company, Baise, Guangxi 533000, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Tobacco Science Research Institute of Baise Tobacco Company, Baise, Guangxi 533000</wicri:regionArea><wicri:noRegion>Guangxi 533000</wicri:noRegion></affiliation></author><author><name sortKey="Lan, Mingxian" sort="Lan, Mingxian" uniqKey="Lan M" first="Mingxian" last="Lan">Mingxian Lan</name><affiliation wicri:level="1"><nlm:affiliation>State Key Laboratory for Conservation and Utilization of Bio-Resources in Yunnan, Yunnan Agricultural University, Kunming 650201, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>State Key Laboratory for Conservation and Utilization of Bio-Resources in Yunnan, Yunnan Agricultural University, Kunming 650201</wicri:regionArea><wicri:noRegion>Kunming 650201</wicri:noRegion></affiliation></author><author><name sortKey="Yang, Jinguang" sort="Yang, Jinguang" uniqKey="Yang J" first="Jinguang" last="Yang">Jinguang Yang</name><affiliation wicri:level="1"><nlm:affiliation>Tobacco Research Institute of the Chinese Academy of Agricultural Sciences, Qingdao, Shandong 266101, China. Electronic address: yangjinguang@caas.cn.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Tobacco Research Institute of the Chinese Academy of Agricultural Sciences, Qingdao, Shandong 266101</wicri:regionArea><wicri:noRegion>Shandong 266101</wicri:noRegion></affiliation></author><author><name sortKey="Wu, Guoxing" sort="Wu, Guoxing" uniqKey="Wu G" first="Guoxing" last="Wu">Guoxing Wu</name><affiliation wicri:level="1"><nlm:affiliation>State Key Laboratory for Conservation and Utilization of Bio-Resources in Yunnan, Yunnan Agricultural University, Kunming 650201, China. Electronic address: wugx1@163.com.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>State Key Laboratory for Conservation and Utilization of Bio-Resources in Yunnan, Yunnan Agricultural University, Kunming 650201</wicri:regionArea><wicri:noRegion>Kunming 650201</wicri:noRegion></affiliation></author></analytic><series><title level="j">Revista Argentina de microbiologia</title><idno type="ISSN">0325-7541</idno></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Carrier Proteins (biosynthesis)</term><term>Carrier Proteins (genetics)</term><term>Cell Membrane Permeability (drug effects)</term><term>Cell Membrane Permeability (genetics)</term><term>Cell Wall (metabolism)</term><term>Fungicides, Industrial (pharmacology)</term><term>Gene Expression Regulation (drug effects)</term><term>Gene Ontology (MeSH)</term><term>Morpholines (pharmacology)</term><term>Oxidative Stress (genetics)</term><term>Phytophthora (drug effects)</term><term>Phytophthora (genetics)</term><term>Plant Diseases (parasitology)</term><term>RNA, Messenger (biosynthesis)</term><term>RNA, Messenger (genetics)</term><term>RNA-Seq (MeSH)</term><term>Reactive Oxygen Species (MeSH)</term><term>Real-Time Polymerase Chain Reaction (MeSH)</term><term>Sequence Alignment (MeSH)</term><term>beta-Glucans (analysis)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>ARN messager (biosynthèse)</term><term>ARN messager (génétique)</term><term>Alignement de séquences (MeSH)</term><term>Espèces réactives de l'oxygène (MeSH)</term><term>Fongicides industriels (pharmacologie)</term><term>Gene Ontology (MeSH)</term><term>Maladies des plantes (parasitologie)</term><term>Morpholines (pharmacologie)</term><term>Paroi cellulaire (métabolisme)</term><term>Perméabilité des membranes cellulaires (effets des médicaments et des substances chimiques)</term><term>Perméabilité des membranes cellulaires (génétique)</term><term>Phytophthora (effets des médicaments et des substances chimiques)</term><term>Phytophthora (génétique)</term><term>Protéines de transport (biosynthèse)</term><term>Protéines de transport (génétique)</term><term>Réaction de polymérisation en chaine en temps réel (MeSH)</term><term>Régulation de l'expression des gènes (effets des médicaments et des substances chimiques)</term><term>Stress oxydatif (génétique)</term><term>bêta-Glucanes (analyse)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="analysis" xml:lang="en"><term>beta-Glucans</term></keywords><keywords scheme="MESH" type="chemical" qualifier="biosynthesis" xml:lang="en"><term>Carrier Proteins</term><term>RNA, Messenger</term></keywords><keywords scheme="MESH" type="chemical" qualifier="genetics" xml:lang="en"><term>Carrier Proteins</term><term>RNA, Messenger</term></keywords><keywords scheme="MESH" qualifier="analyse" xml:lang="fr"><term>bêta-Glucanes</term></keywords><keywords scheme="MESH" qualifier="biosynthèse" xml:lang="fr"><term>ARN messager</term><term>Protéines de transport</term></keywords><keywords scheme="MESH" qualifier="drug effects" xml:lang="en"><term>Cell Membrane Permeability</term><term>Gene Expression Regulation</term><term>Phytophthora</term></keywords><keywords scheme="MESH" qualifier="effets des médicaments et des substances chimiques" xml:lang="fr"><term>Perméabilité des membranes cellulaires</term><term>Phytophthora</term><term>Régulation de l'expression des gènes</term></keywords><keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Cell Membrane Permeability</term><term>Oxidative Stress</term><term>Phytophthora</term></keywords><keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>ARN messager</term><term>Perméabilité des membranes cellulaires</term><term>Phytophthora</term><term>Protéines de transport</term><term>Stress oxydatif</term></keywords><keywords scheme="MESH" qualifier="metabolism" xml:lang="en"><term>Cell Wall</term></keywords><keywords scheme="MESH" qualifier="métabolisme" xml:lang="fr"><term>Paroi cellulaire</term></keywords><keywords scheme="MESH" qualifier="parasitologie" xml:lang="fr"><term>Maladies des plantes</term></keywords><keywords scheme="MESH" qualifier="parasitology" xml:lang="en"><term>Plant Diseases</term></keywords><keywords scheme="MESH" qualifier="pharmacologie" xml:lang="fr"><term>Fongicides industriels</term><term>Morpholines</term></keywords><keywords scheme="MESH" type="chemical" qualifier="pharmacology" xml:lang="en"><term>Fungicides, Industrial</term><term>Morpholines</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Gene Ontology</term><term>RNA-Seq</term><term>Reactive Oxygen Species</term><term>Real-Time Polymerase Chain Reaction</term><term>Sequence Alignment</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Alignement de séquences</term><term>Espèces réactives de l'oxygène</term><term>Gene Ontology</term><term>Réaction de polymérisation en chaine en temps réel</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Phytophthora parasitica is an important oomycete that causes disease in a variety of plants, dimethomorph fungicides being specific for oomycetes. The aim of this study was to use RNA-seq to rapidly discover the mechanism by which dimethomorph acts in the treatment of P. parasitica. We found that the expression of 832 genes changed significantly after the dimethomorph treatment, including 365 up-regulated genes and 467 down-regulated genes. According to the Gene Ontology (GO) enrichment analysis, pathway enrichment and verification test results, the following conclusions are obtained: (i) the treatment of P. parasitica with dimethomorph causes changes in the expression levels of genes associated with the cell wall and cell wall synthesis; (ii) dimethomorph treatment results in reduced permeability of the cell membrane and changes in the expression of certain transport-related proteins; (iii) dimethomorph treatment increased reactive oxygen species and reduced the expression of genes related to the control of oxidative stress.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">30670299</PMID><DateCompleted><Year>2020</Year><Month>03</Month><Day>02</Day></DateCompleted><DateRevised><Year>2020</Year><Month>03</Month><Day>02</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Print">0325-7541</ISSN><JournalIssue CitedMedium="Internet"><Volume>51</Volume><Issue>3</Issue><PubDate><MedlineDate>2019 Jul - Sep</MedlineDate></PubDate></JournalIssue><Title>Revista Argentina de microbiologia</Title><ISOAbbreviation>Rev Argent Microbiol</ISOAbbreviation></Journal><ArticleTitle>RNA-seq analysis of the response of plant-pathogenic oomycete Phytophthora parasitica to the fungicide dimethomorph.</ArticleTitle><Pagination><MedlinePgn>268-277</MedlinePgn></Pagination><ELocationID EIdType="pii" ValidYN="Y">S0325-7541(18)30117-2</ELocationID><ELocationID EIdType="doi" ValidYN="Y">10.1016/j.ram.2018.08.007</ELocationID><Abstract><AbstractText>Phytophthora parasitica is an important oomycete that causes disease in a variety of plants, dimethomorph fungicides being specific for oomycetes. The aim of this study was to use RNA-seq to rapidly discover the mechanism by which dimethomorph acts in the treatment of P. parasitica. We found that the expression of 832 genes changed significantly after the dimethomorph treatment, including 365 up-regulated genes and 467 down-regulated genes. According to the Gene Ontology (GO) enrichment analysis, pathway enrichment and verification test results, the following conclusions are obtained: (i) the treatment of P. parasitica with dimethomorph causes changes in the expression levels of genes associated with the cell wall and cell wall synthesis; (ii) dimethomorph treatment results in reduced permeability of the cell membrane and changes in the expression of certain transport-related proteins; (iii) dimethomorph treatment increased reactive oxygen species and reduced the expression of genes related to the control of oxidative stress.</AbstractText><CopyrightInformation>Copyright © 2018 Asociación Argentina de Microbiología. Publicado por Elsevier España, S.L.U. All rights reserved.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Hao</LastName><ForeName>Kaiqiang</ForeName><Initials>K</Initials><AffiliationInfo><Affiliation>State Key Laboratory for Conservation and Utilization of Bio-Resources in Yunnan, Yunnan Agricultural University, Kunming 650201, China; Tobacco Research Institute of the Chinese Academy of Agricultural Sciences, Qingdao, Shandong 266101, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lin</LastName><ForeName>Beisen</ForeName><Initials>B</Initials><AffiliationInfo><Affiliation>Tobacco Science Research Institute of Baise Tobacco Company, Baise, Guangxi 533000, China; Hainan Provincial Branch of China National Tobacco Corporation, Haikou, Hainan, 571100, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Nian</LastName><ForeName>Fuzhao</ForeName><Initials>F</Initials><AffiliationInfo><Affiliation>State Key Laboratory for Conservation and Utilization of Bio-Resources in Yunnan, Yunnan Agricultural University, Kunming 650201, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Gao</LastName><ForeName>Xi</ForeName><Initials>X</Initials><AffiliationInfo><Affiliation>State Key Laboratory for Conservation and Utilization of Bio-Resources in Yunnan, Yunnan Agricultural University, Kunming 650201, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Wei</LastName><ForeName>Zhong</ForeName><Initials>Z</Initials><AffiliationInfo><Affiliation>Tobacco Science Research Institute of Baise Tobacco Company, Baise, Guangxi 533000, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Luo</LastName><ForeName>Gang</ForeName><Initials>G</Initials><AffiliationInfo><Affiliation>Tobacco Science Research Institute of Baise Tobacco Company, Baise, Guangxi 533000, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lu</LastName><ForeName>Yachun</ForeName><Initials>Y</Initials><AffiliationInfo><Affiliation>Tobacco Science Research Institute of Baise Tobacco Company, Baise, Guangxi 533000, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lan</LastName><ForeName>Mingxian</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>State Key Laboratory for Conservation and Utilization of Bio-Resources in Yunnan, Yunnan Agricultural University, Kunming 650201, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Yang</LastName><ForeName>Jinguang</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Tobacco Research Institute of the Chinese Academy of Agricultural Sciences, Qingdao, Shandong 266101, China. Electronic address: yangjinguang@caas.cn.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Wu</LastName><ForeName>Guoxing</ForeName><Initials>G</Initials><AffiliationInfo><Affiliation>State Key Laboratory for Conservation and Utilization of Bio-Resources in Yunnan, Yunnan Agricultural University, Kunming 650201, China. Electronic address: wugx1@163.com.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D003160">Comparative Study</PublicationType><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2019</Year><Month>01</Month><Day>19</Day></ArticleDate></Article><MedlineJournalInfo><Country>Argentina</Country><MedlineTA>Rev Argent Microbiol</MedlineTA><NlmUniqueID>8002834</NlmUniqueID><ISSNLinking>0325-7541</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D002352">Carrier Proteins</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D005659">Fungicides, Industrial</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D009025">Morpholines</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D012333">RNA, Messenger</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D017382">Reactive Oxygen Species</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D047071">beta-Glucans</NameOfSubstance></Chemical><Chemical><RegistryNumber>3EXL2158GV</RegistryNumber><NameOfSubstance UI="C076154">dimethomorph</NameOfSubstance></Chemical><Chemical><RegistryNumber>9051-97-2</RegistryNumber><NameOfSubstance UI="C033363">beta-1,3-glucan</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D002352" MajorTopicYN="N">Carrier Proteins</DescriptorName><QualifierName UI="Q000096" MajorTopicYN="N">biosynthesis</QualifierName><QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D002463" MajorTopicYN="N">Cell Membrane Permeability</DescriptorName><QualifierName UI="Q000187" MajorTopicYN="N">drug effects</QualifierName><QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D002473" MajorTopicYN="N">Cell Wall</DescriptorName><QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D005659" MajorTopicYN="N">Fungicides, Industrial</DescriptorName><QualifierName UI="Q000494" MajorTopicYN="Y">pharmacology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D005786" MajorTopicYN="N">Gene Expression Regulation</DescriptorName><QualifierName UI="Q000187" MajorTopicYN="N">drug effects</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D063990" MajorTopicYN="N">Gene Ontology</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D009025" MajorTopicYN="N">Morpholines</DescriptorName><QualifierName UI="Q000494" MajorTopicYN="Y">pharmacology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D018384" MajorTopicYN="N">Oxidative Stress</DescriptorName><QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D010838" MajorTopicYN="N">Phytophthora</DescriptorName><QualifierName UI="Q000187" MajorTopicYN="Y">drug effects</QualifierName><QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D010935" MajorTopicYN="N">Plant Diseases</DescriptorName><QualifierName UI="Q000469" MajorTopicYN="N">parasitology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D012333" MajorTopicYN="N">RNA, Messenger</DescriptorName><QualifierName UI="Q000096" MajorTopicYN="Y">biosynthesis</QualifierName><QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D000081246" MajorTopicYN="Y">RNA-Seq</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D017382" MajorTopicYN="N">Reactive Oxygen Species</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D060888" MajorTopicYN="N">Real-Time Polymerase Chain Reaction</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D016415" MajorTopicYN="N">Sequence Alignment</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D047071" MajorTopicYN="N">beta-Glucans</DescriptorName><QualifierName UI="Q000032" MajorTopicYN="N">analysis</QualifierName></MeshHeading></MeshHeadingList><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">Dimethomorph</Keyword><Keyword MajorTopicYN="N">Dimetomorf</Keyword><Keyword MajorTopicYN="N">Phytophthora parasitica</Keyword><Keyword MajorTopicYN="N">RNA-seq</Keyword></KeywordList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2018</Year><Month>03</Month><Day>27</Day></PubMedPubDate><PubMedPubDate PubStatus="revised"><Year>2018</Year><Month>07</Month><Day>31</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2018</Year><Month>08</Month><Day>26</Day></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2019</Year><Month>1</Month><Day>24</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2020</Year><Month>3</Month><Day>3</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2019</Year><Month>1</Month><Day>24</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">30670299</ArticleId><ArticleId IdType="pii">S0325-7541(18)30117-2</ArticleId><ArticleId IdType="doi">10.1016/j.ram.2018.08.007</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>République populaire de Chine</li></country></list><tree><country name="République populaire de Chine"><noRegion><name sortKey="Hao, Kaiqiang" sort="Hao, Kaiqiang" uniqKey="Hao K" first="Kaiqiang" last="Hao">Kaiqiang Hao</name></noRegion><name sortKey="Gao, Xi" sort="Gao, Xi" uniqKey="Gao X" first="Xi" last="Gao">Xi Gao</name><name sortKey="Lan, Mingxian" sort="Lan, Mingxian" uniqKey="Lan M" first="Mingxian" last="Lan">Mingxian Lan</name><name sortKey="Lin, Beisen" sort="Lin, Beisen" uniqKey="Lin B" first="Beisen" last="Lin">Beisen Lin</name><name sortKey="Lu, Yachun" sort="Lu, Yachun" uniqKey="Lu Y" first="Yachun" last="Lu">Yachun Lu</name><name sortKey="Luo, Gang" sort="Luo, Gang" uniqKey="Luo G" first="Gang" last="Luo">Gang Luo</name><name sortKey="Nian, Fuzhao" sort="Nian, Fuzhao" uniqKey="Nian F" first="Fuzhao" last="Nian">Fuzhao Nian</name><name sortKey="Wei, Zhong" sort="Wei, Zhong" uniqKey="Wei Z" first="Zhong" last="Wei">Zhong Wei</name><name sortKey="Wu, Guoxing" sort="Wu, Guoxing" uniqKey="Wu G" first="Guoxing" last="Wu">Guoxing Wu</name><name sortKey="Yang, Jinguang" sort="Yang, Jinguang" uniqKey="Yang J" first="Jinguang" last="Yang">Jinguang Yang</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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